Berberine hydrochloric acid, alias berberine, is a kind of active alkaloid extracted from the roots of Coptis chinensis, Phellodendron chinense and three needles, which has the functions of clearing away heat, detoxification, purging fire and so on. It is widely used in traditional Chinese medicine. It was originally used in clinic and mainly played an antibacterial role. As an effective component in the treatment of gastrointestinal inflammation, it also showed good curative effect in the treatment of diarrhea caused by dysentery and irritable bowel syndrome. And has been widely used as an over-the-counter drug for the prevention and treatment of dysentery. At the same time, it also plays a significant role in regulating blood glucose and lipid metabolism, preventing atherosclerosis, antiarrhythmic, inhibiting tumor cell proliferation, antivirus and so on.