5-HTP Powder: Nature's Serotonin Precursor
Our 5-HTP Powder (5-Hydroxytryptophan) is a premium bioactive ingredient derived from the seeds of Griffonia simplicifolia, a plant native to West Africa. As a direct precursor to serotonin, 5-HTP plays a crucial role in supporting emotional wellbeing, sleep regulation, and appetite control.
Using our proprietary low-temperature extraction process, we preserve the natural bioactivity of 5-HTP while achieving an exceptional purity level of 99% or higher. This results in a fine, off-white powder that dissolves easily in water and ethanol, making it ideal for various formulations.
Our 5-HTP Powder is meticulously tested to ensure it meets the highest pharmaceutical standards, free from heavy metals, pesticides, and solvent residues. It is trusted by leading nutraceutical companies, pharmaceutical manufacturers, and functional food producers worldwide.
Pharmaceutical Grade
Meets USP, EP, and FCC standards, ensuring suitability for the most demanding applications.
Natural Sourcing
Derived from sustainably harvested Griffonia simplicifolia seeds from certified plantations.
Scientifically Verified
Backed by extensive research confirming its role in supporting mood and sleep health.
Product Specifications
| Parameter | Specification | Test Method | Standard |
|---|---|---|---|
| 5-HTP Content | ≥99.0% | HPLC | USP <561> |
| Appearance | Off-white to white fine powder | Visual inspection | FCC VI |
| Mesh Size | 80-100 mesh (95% passing) | Sieve analysis | ISO 13314 |
| Solubility | ≥95% in water; ≥98% in ethanol | Solubility test | USP <1236> |
| Loss on Drying | ≤0.5% | TGA (105°C, 2hrs) | EP 2.2.32 |
| Heavy Metals | Pb ≤0.01ppm; Cd ≤0.005ppm; As ≤0.005ppm | ICP-MS | USP <231>, ICH Q3D |
| Microbial Count | Total plate count ≤1,000cfu/g; E. coli/Salmonella: Negative | Plate count agar | USP <61> |
| Shelf Life | 36 months (proper storage) | Stability testing | ISO 11074 |
Why Choose Our 5-HTP Powder?
High Purity 5-HTP Powder for Supplements
Ultra-High Purity
≥99% 5-HTP content (HPLC verified) – the highest purity available in the market, ensuring maximum efficacy in your formulations.
Bioactivity Preserved
Our proprietary low-temperature extraction process (≤50°C) maintains 5-HTP's natural structure and bioactivity, unlike high-heat methods.
Global Compliance
Meets USP, EP, FCC, and ICH standards. Certified GMP, Kosher, and Halal, enabling access to markets worldwide.
Premium Sourcing
Derived from select Griffonia simplicifolia seeds grown in optimal conditions, ensuring high natural 5-HTP content.
Consistent Quality
Strict quality control measures ensure batch-to-batch consistency, with every lot tested for purity, potency, and safety.
Easy Formulation
Excellent solubility in water and ethanol, with ideal particle size (80-100 mesh) for easy integration into various product forms.
5-HTP Powder Applications
Griffonia simplicifolia Extract 99% 5-HTP
Nutraceutical Supplements
5-HTP Powder is widely used in dietary supplements formulated to support:
- Mood regulation and emotional wellbeing
- Healthy sleep patterns and restful sleep
- Appetite control and weight management
- Stress response and relaxation
Our 5-HTP Powder is ideal for capsules, tablets, and powder blends, often combined with vitamins B6, magnesium, or L-tryptophan to enhance absorption and efficacy.
Pharmaceutical Formulations
Pharmaceutical companies utilize our high-purity 5-HTP Powder in formulations targeting mild mood disorders, sleep disturbances, and certain neurological conditions. Its consistent quality and high purity make it suitable for clinical applications requiring precise dosing.
Functional Foods & Beverages
5-HTP Powder is incorporated into functional foods and beverages such as:
- Relaxation-promoting herbal teas
- Sleep-supporting nighttime beverages
- Mood-balancing protein bars
- Wellness-focused powdered drink mixes
Research Applications
Our 5-HTP Powder is trusted by academic institutions and research laboratories for studies on serotonin metabolism, neuropharmacology, and psychological wellbeing due to its exceptional purity and consistency.
Our Competitive Advantages
25+ Years of Expertise
Specialized in 5-HTP extraction and purification since 2008, with a dedicated R&D team holding 3 patents in bioactive compound isolation.
Controlled Supply Chain
Direct partnerships with Griffonia simplicifolia growers ensure consistent raw material quality and sustainable harvesting practices.
Certified Facilities
FDA-registered, GMP-certified production facilities with ISO 9001 and ISO 13485 certifications for pharmaceutical-grade manufacturing.
Advanced Testing Lab
In-house laboratory equipped with HPLC, ICP-MS, and microbial testing capabilities to ensure every batch meets our strict standards.
Customization Capabilities
Ability to provide tailored 5-HTP concentrations (from 50% to 99%), particle sizes, and formulations to meet specific customer requirements.
Global Distribution
Exporting to 45+ countries with regulatory support for local market approvals, including FDA DMF, EU CEP, and health claims assistance.
Success Stories
"After switching to this 5-HTP Powder, our mood support supplement saw a 40% increase in positive customer reviews citing improved efficacy. The consistent quality has simplified our production process."
Product: Mood Balance Capsules
Result: 35% sales growth in 6 months
"The 99% purity of this 5-HTP Powder was crucial for our clinical formulation. Their comprehensive documentation package helped us achieve regulatory approval 3 months faster than anticipated."
Product: Prescription sleep aid
Result: Successfully launched in 12 EU countries
"This 5-HTP Powder dissolved perfectly in our nighttime relaxation drink. Consumer testing showed 82% reported better sleep quality, making it our best-selling new product of the year."
Product: Sleep Well Herbal Beverage
Result: 18% market share within 3 months
Quality Control Measures
Our 5-HTP Powder undergoes rigorous quality control at every stage of production, ensuring it meets the highest standards of purity, safety, and consistency.
Raw Material Inspection
All Griffonia simplicifolia seeds are tested upon arrival for:
- Natural 5-HTP content (minimum 12%)
- Heavy metal contamination (ICP-MS)
- Pesticide residues (GC-MS)
- Microbial contamination
In-Process Quality Control
Critical process parameters are monitored and recorded throughout production:
- Extraction temperature (constantly monitored to stay ≤50°C)
- Purification efficiency (tested hourly via HPLC)
- Moisture content during drying stages
- Particle size distribution after milling
Final Product Testing
Every batch of 5-HTP Powder undergoes extensive testing before release:
- 5-HTP purity (≥99% by HPLC)
- Heavy metals (Pb, Cd, As below 0.01ppm by ICP-MS)
- Residual solvents (below ICH Q3C limits by GC-FID)
- Microbial counts (total plate count ≤1,000cfu/g)
- Identity confirmation (IR spectroscopy)
- Stability testing (accelerated conditions)
Documentation & Traceability
Each batch is accompanied by a comprehensive Certificate of Analysis (COA) and full traceability documentation from seed sourcing to finished product. We maintain batch records for a minimum of 5 years.
Customer Reviews
Dr. Robert Chen
R&D Director, NutraScience Labs
Sarah Johnson
Quality Manager, WellnessFormulations
Marco Rossi
Procurement Director, PharmaVital EU
Frequently Asked Questions
What is 5-HTP Powder?
5-HTP (5-Hydroxytryptophan) Powder is a naturally occurring amino acid derivative extracted from the seeds of Griffonia simplicifolia. It serves as a precursor to serotonin, a neurotransmitter that plays a key role in regulating mood, sleep, and appetite. Our 5-HTP Powder is a high-purity (≥99%) ingredient used in nutritional supplements, pharmaceuticals, and functional foods.
What is the purity of your 5-HTP Powder?
Our 5-HTP Powder consistently tests at 99% purity or higher, verified by high-performance liquid chromatography (HPLC). This is significantly higher than the industry standard of 98% for pharmaceutical-grade 5-HTP, ensuring maximum efficacy in your formulations.
Is your 5-HTP Powder suitable for pharmaceutical use?
Yes, our 5-HTP Powder meets the strict requirements for pharmaceutical applications. It is produced in FDA-registered, GMP-certified facilities and complies with USP, EP, and ICH guidelines. We provide comprehensive documentation, including DMF files, to support pharmaceutical regulatory submissions.
What are the shipping and lead time options?
We offer flexible shipping options to meet your needs:
Samples and small orders (100g-5kg): Shipped via DHL/FedEx with 3-7 business day delivery
Bulk orders (25kg+): Available via air freight (7-10 days) or sea freight (20-30 days)
Standard lead times are 3-5 business days for standard products. Custom formulations may require additional time depending on specifications.
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